Skip to main content

Physical Stress Signaling

Meaning

Physical Stress Signaling describes the cascade of biochemical and neuroendocrine events initiated in response to acute, non-pathological physical challenges, such as intense, structured exercise, controlled thermal exposure, or brief, intermittent fasting. This controlled, transient stress, often clinically referred to as hormesis, actively activates cellular defense mechanisms and adaptive pathways that ultimately strengthen the entire organism. The body’s intrinsic ability to efficiently initiate and terminate this signaling is a primary marker of its systemic resilience and vitality.