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Photolysis

Meaning

Photolysis is a fundamental chemical process in which a molecule is broken down into smaller fragments, atoms, or free radicals through the direct absorption of light energy, specifically photons. In the context of biological and hormonal health, this reaction is a critical concern for the stability and potency of pharmaceutical compounds, especially peptides and hormones stored in solution. Exposure to light, particularly ultraviolet (UV) radiation, can induce photolytic degradation, compromising the drug’s structural integrity and therapeutic efficacy. This principle underscores the clinical requirement for storing light-sensitive medications in opaque vials and away from direct light sources.