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Phosphoinositides

Meaning

A small but critically important class of phospholipids, which are lipid signaling molecules derived from phosphatidylinositol, located primarily on the inner leaflet of cellular membranes. They are master regulators of cellular signaling, existing in seven different phosphorylated species based on the phosphorylation state of the inositol ring. Phosphoinositides act as membrane-bound docking sites for a multitude of signaling proteins. Their rapid interconversion allows for precise temporal and spatial regulation within the cell.