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Phosphoinositide Signaling

Meaning

Phosphoinositide Signaling is a ubiquitous and fundamental cellular communication pathway involving the metabolism of specific lipid molecules, the phosphoinositides, which are integral components of the inner leaflet of the cell membrane. This pathway is a critical second messenger system activated by numerous hormones and growth factors that bind to cell surface receptors. The cascade results in the rapid generation of secondary messengers that propagate the initial external signal throughout the cell. This signaling is essential for regulating a vast array of cellular processes, including growth, secretion, and metabolism.