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Phosphatidylinositol Signaling

Meaning

A ubiquitous and highly conserved intracellular communication system centered on the regulated phosphorylation and dephosphorylation of phosphatidylinositol lipids embedded in the cell membrane. This signaling pathway is a crucial mediator for the actions of numerous hormones, growth factors, and neurotransmitters, linking their external binding to receptors with specific internal cellular responses. The integrity of this cascade is vital for processes such as cell growth, metabolism, and membrane trafficking.