The method of titrating therapeutic agents, particularly hormones or biologics, to an individual’s unique pharmacokinetic profile and desired physiological endpoint, rather than relying on population averages.
Origin
This precision reflects the maturation of pharmacodynamics, emphasizing the biological variability in drug response influenced by genetics, metabolism, and current hormonal milieu.
Mechanism
Dosing relies on frequent monitoring of target analytes and clinical response, employing algorithms to adjust frequency and quantity, thereby maximizing therapeutic effect while minimizing off-target receptor exposure.
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