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Pharmacological Optimization

Meaning

Pharmacological Optimization is the precise clinical strategy of adjusting the dose, frequency, and route of administration for therapeutic agents, including hormones and peptides, to achieve the maximal desired physiological effect with the lowest possible risk of adverse outcomes. This process is a continuous, data-driven refinement of a patient’s therapeutic regimen. It moves beyond standard dosing guidelines to personalize treatment based on an individual’s unique metabolic and endocrine response. The goal is to maximize the therapeutic index.