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Pharmacokinetics of Injectable Hormones

Meaning

The pharmacokinetics of injectable hormones is the study of how the body handles hormones administered via injection, specifically tracking their absorption, distribution, metabolism, and excretion (ADME). This analysis is crucial for determining the optimal dosing schedule and injection frequency for hormonal therapies, such as testosterone or estrogen injections, to maintain stable, therapeutic blood levels. Understanding the kinetics of a particular esterified hormone is necessary to predict the time to peak concentration and the duration of its biological effect. Clinical practice relies on this data to minimize supraphysiological spikes and sub-therapeutic troughs.