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Pharmacokinetic Response

Meaning

Pharmacokinetic Response describes the dynamic processes that dictate how a pharmaceutical agent or exogenous hormone is absorbed, distributed, metabolized, and excreted (ADME) by the body over time. This response is highly individualized, influencing the drug’s concentration at its site of action and, consequently, its therapeutic efficacy and potential for adverse effects. Clinically, understanding a patient’s pharmacokinetic response is essential for personalized medicine, enabling precise dosing and scheduling to maintain optimal therapeutic concentrations. It is a fundamental concept in drug development and clinical practice.