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Pharmacokinetic Principles

Meaning

Pharmacokinetic principles are the fundamental scientific concepts that quantitatively describe the relationship between the administered dosage of a therapeutic agent and its concentration profile within the body over a specified period. This discipline encompasses the critical processes of absorption, distribution, metabolism, and excretion (ADME). Understanding these principles is absolutely essential for clinical practice, enabling the precise calculation of optimal dosing regimens to achieve therapeutic efficacy while meticulously minimizing systemic toxicity. This scientific discipline underpins the rational and safe use of all hormonal and peptide therapies.