What is the Origin of Pharmacokinetic Mapping?

The term is derived from the field of pharmacokinetics, a branch of pharmacology that studies the mathematical models of drug movement. The "mapping" aspect refers to the graphical or data-driven representation of these variables in a personalized manner, moving beyond generalized population averages. This data-driven approach is essential for Bio-Precision Therapy.

What is the Mechanism of Pharmacokinetic Mapping?

The mechanism involves collecting serial blood or saliva samples following drug administration and analyzing the concentration of the parent compound and its active metabolites using clinical-grade tools. This data allows the practitioner to calculate key parameters like half-life and clearance rate. By adjusting the dose and frequency based on this map, the clinician can ensure that the patient maintains the optimal concentration range required for sustained endocrine coherence or targeted neuroprotective actions.

Pharmacokinetic Mapping

Meaning

Pharmacokinetic mapping is the precise clinical analysis and visualization of a therapeutic agent’s absorption, distribution, metabolism, and excretion (ADME) within an individual patient’s physiological system. This process quantifies the time-course of the drug’s concentration in the body, providing essential data to customize dosing and delivery schedules. It is a cornerstone of individualized therapy to ensure optimal therapeutic windows are consistently maintained.