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Pharmacogenomics in Endocrinology

Meaning

Pharmacogenomics in Endocrinology is the clinical application of an individual’s genetic profile to predict their response to endocrine-related medications, including hormone replacement therapies and modulatory agents. This field analyzes genetic variations, particularly single nucleotide polymorphisms (SNPs) in genes coding for drug-metabolizing enzymes and hormone receptors, to anticipate efficacy and potential adverse drug reactions. By integrating genomic data with clinical parameters, clinicians can move toward true precision medicine, customizing hormone doses and selecting the most appropriate compounds for each patient, thereby optimizing therapeutic outcomes and minimizing risks.