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Pharmacogenetic Optimization

Meaning

Pharmacogenetic Optimization is a clinical strategy that uses an individual’s genetic information to predict their response to specific medications, hormones, or therapeutic compounds, thereby tailoring dosage and selection for maximum efficacy and minimal adverse effects. This practice analyzes variants in genes that code for drug-metabolizing enzymes, drug transporters, and drug targets to create a precision treatment plan. The goal is to move beyond trial-and-error prescribing to a data-driven approach that ensures the right therapeutic agent is delivered at the correct concentration. This is particularly relevant in hormonal health, where synthetic hormones and modulators are frequently used.