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Pharmacodynamics of Substitution

Meaning

Pharmacodynamics of Substitution describes the study of the biochemical and physiological effects of administered exogenous substances, typically bioidentical hormones, on the body’s target tissues and overall endocrine system. This field specifically examines how the substituted hormone interacts with receptors, influences downstream signaling, and affects the endogenous production of hormones. Understanding these dynamics is crucial for personalizing dosing to achieve therapeutic goals while minimizing unintended systemic consequences.