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Pharmacodynamics of Peptide Action

Meaning

Pharmacodynamics of peptide action refers to the detailed study of how a therapeutic peptide drug interacts with its biological targets and produces its physiological effects in the body. This includes understanding the binding affinity to specific receptors, the resulting intracellular signaling cascades, and the ultimate systemic response, such as increased hormone secretion or metabolic change. Clinical knowledge of pharmacodynamics is essential for determining the correct dosing, frequency, and route of administration to achieve the desired therapeutic outcome. It is the core principle of rational peptide therapy.