The Pharmacodynamics of Neuro-Peptides is the study of the biochemical and physiological effects exerted by small protein signaling molecules that function as both neurotransmitters and hormones within the nervous and endocrine systems. Their action is multifaceted and powerful. We examine their effect profile.
Origin
This area is a specialized sub-discipline of pharmacology, focusing specifically on peptide-based messengers that are critical for inter-system communication, often crossing or influencing the blood-brain barrier dynamics. They are the body’s subtle communicators.
Mechanism
Neuro-peptides exert their effects primarily by binding to specific G-protein coupled receptors or ligand-gated ion channels on target cells. This binding initiates intracellular second messenger responses that ultimately alter neuronal excitability or regulate glandular secretion rates.
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