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Pharmacodynamic Marker Interpretation

Meaning

The systematic evaluation of biochemical or physiological indicators that directly reflect the effect of a therapeutic intervention on the body, rather than simply measuring the drug’s concentration. These pharmacodynamic markers assess the target tissue response, such as receptor occupancy, enzyme activity modulation, or downstream signaling changes, to determine if the drug is working as intended at the cellular level. This interpretation is vital for optimizing dosing and confirming biological efficacy in personalized treatment.