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Pharmacodynamic Effect

Meaning

The Pharmacodynamic Effect describes the specific biochemical or physiological alteration induced in a biological system subsequent to the interaction of a compound with its molecular target, such as a receptor or enzyme. This effect is concerned with what the substance does to the body, rather than what the body does to the substance. In hormonal contexts, this relates to how an exogenous compound modifies the normal signaling profile of an endocrine axis. Understanding this effect is vital for predicting therapeutic outcomes.