Skip to main content

PGC1alpha Regulation

Meaning

PGC1alpha Regulation refers to the control mechanisms governing the expression and activity of Peroxisome Proliferator-Activated Receptor gamma Coactivator 1-alpha, a master transcriptional coactivator protein. This protein is a central hub for energy metabolism, fundamentally orchestrating mitochondrial biogenesis and adaptive thermogenesis in tissues like skeletal muscle and brown adipose tissue. Optimizing its regulation is a key therapeutic target for enhancing metabolic flexibility and physical endurance.