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Perimenopause Hormones

Meaning

Perimenopause Hormones refers to the specific, fluctuating endocrine messengers that characterize the transitional phase leading up to the final cessation of menstrual cycles, a period known as perimenopause. This stage is defined by significant shifts in the hypothalamic-pituitary-ovarian axis, primarily manifesting as unpredictable, often dramatic changes in circulating Estradiol and Progesterone levels due to declining ovarian follicular function. Follicle-Stimulating Hormone (FSH) and Luteinizing Hormone (LH) levels also begin to rise as the pituitary attempts to compensate for the diminishing ovarian response. Understanding the precise profile of these hormones is essential for diagnosing the stage of reproductive aging and managing the associated clinical symptoms, such as vasomotor instability and sleep disturbances.