What is the Origin of Perimenopause Hormone Support?

The term is rooted in women's health and endocrinology, recognizing perimenopause as the distinct period leading up to the final menstrual period, characterized by significant hormonal variability. The need for 'support' arose from the clinical observation that symptoms during this phase are often more challenging than those in established menopause due to extreme hormonal fluctuations.

What is the Mechanism of Perimenopause Hormone Support?

The primary hormonal imbalance in perimenopause involves declining and erratic progesterone production, often accompanied by fluctuating estrogen levels. Hormone support works by providing stable, supplemental levels of these hormones, counteracting the effects of endogenous dysregulation. Progesterone stabilizes the menstrual cycle and mitigates endometrial hyperplasia, while low-dose estrogen can address severe hot flashes and mood swings, acting on central nervous system and peripheral receptors.

Perimenopause Hormone Support

Meaning

Perimenopause Hormone Support is the clinical intervention strategy involving the use of hormone therapy, often bioidentical hormones like progesterone or low-dose estrogen, to alleviate the vasomotor, psychological, and menstrual symptoms associated with the perimenopausal transition. This support aims to stabilize the fluctuating hormone levels characteristic of this phase, improving quality of life and managing the unpredictable nature of the hypothalamic-pituitary-ovarian axis decline. Treatment is tailored to the individual’s symptom profile and remaining ovarian function.