The proactive, data-informed clinical management of the physiological instability that characterizes the perimenopausal transition preceding menopause. This engineering aims to buffer the system against significant and often rapid fluctuations in ovarian hormone output. We seek to maintain systemic stability during this period of endocrine flux.
Origin
This term applies engineering principles to the inherently volatile endocrine environment of the late reproductive years. It recognizes that managing the transition effectively prevents long-term downstream health consequences.
Mechanism
Strategies focus on stabilizing the endocrine feedback loops, particularly buffering the HPA axis against erratic estrogen withdrawal signals. Interventions may involve targeted support for bone mineral density maintenance and metabolic regulation. The goal is to manage the fluctuating hormonal signals to minimize disruptive symptoms and protect tissue health until stable postmenopausal levels are established.
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