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Peri-Menopausal Hormone Sequencing

Meaning

Peri-Menopausal Hormone Sequencing is a carefully timed, step-wise clinical strategy for managing the hormonal fluctuations characteristic of the transition phase leading up to menopause. This sequencing involves the strategic introduction and titration of specific hormones, typically estrogen and progesterone, in a defined order based on symptom presentation. The objective is to manage the declining ovarian function smoothly, mitigating vasomotor symptoms and preserving bone density without inducing undesirable side effects. This requires dynamic clinical judgment.