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Performance Limiting Biomarkers

Meaning

Performance Limiting Biomarkers are quantifiable physiological or biochemical indicators whose suboptimal levels or dysregulation directly correlate with a measurable reduction in an individual’s physical, cognitive, or metabolic performance capacity. These markers move beyond standard disease diagnostics to identify specific subclinical deficiencies that prevent an individual from achieving peak functional status. Examples include elevated inflammatory markers, chronic low-grade cortisol excess, or low free thyroid hormone levels. Identifying and correcting these biomarkers is central to personalized health optimization and longevity medicine.