What is the Origin of Performance Geroscience?

This field represents a modern fusion of sports science, longevity research, and clinical endocrinology, moving beyond simple lifespan extension to encompass 'high-performance aging.' It is driven by the demand for sustained physical and mental output well into later life. The term signifies a proactive, function-first strategy against biological decline.

What is the Mechanism of Performance Geroscience?

Interventions are centered on preserving youthful mitochondrial function, maintaining telomere length, and sustaining robust hormonal signaling, particularly the anabolic-to-catabolic ratio. This involves strategies to combat cellular senescence and oxidative stress, which impair performance. By optimizing the endocrine environment, such as supporting healthy testosterone and IGF-1 levels, Performance Geroscience aims to ensure the cellular machinery remains capable of peak metabolic and regenerative output.

Performance Geroscience

Meaning

Performance Geroscience is a specialized sub-discipline that applies the principles of geroscience—the study of the biology of aging—to the optimization of human physical and cognitive performance across the lifespan. It focuses on interventions that not only slow biological aging but also enhance peak functional capacity and resilience. This approach views age-related decline as a malleable biological process.