The proactive clinical strategy designed to prevent the regression of previously achieved peak physiological or cognitive function, often following an intensive optimization phase. This maintenance phase focuses on sustaining the established hormonal equilibrium against the constant forces of physiological entropy. It is about preserving the achieved anabolic state.
Origin
This concept arises from the clinical observation that without ongoing targeted support, physiological gains achieved through intensive protocols tend to revert toward a less optimal baseline. Maintenance ensures the continued efficacy of the endocrine system under chronic load. The ceiling denotes the highest attainable functional level.
Mechanism
Maintenance protocols involve carefully timed, often lower-dose, administration of modulators to keep key endocrine signals, like IGF-1 or free testosterone, within the high-normal range established during calibration. This strategy supports the ongoing need for cellular turnover and adaptation without inducing receptor desensitization. Sustaining positive nitrogen balance and adequate mitochondrial output are key physiological markers tracked.
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