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PER2

Meaning

PER2, or Period Circadian Regulator 2, is a gene that encodes a protein which is a core component of the molecular circadian clock, the intrinsic timekeeping system found in nearly all human cells. This clock regulates daily physiological rhythms, including the sleep-wake cycle, body temperature, blood pressure, and critical aspects of endocrine and metabolic function. Proper PER2 gene expression is essential for synchronizing the body’s internal processes with the 24-hour external environment, ensuring metabolic and hormonal events occur at their optimal biological time.