The clinical application of synthetic or naturally derived peptides to precisely influence specific molecular targets, often receptors or enzyme active sites, to achieve a desired endocrine or metabolic outcome. This involves leveraging the specificity inherent in peptide signaling molecules.
Origin
This originates in pharmacology and biotechnology, utilizing peptides—short chains of amino acids—as highly specific signaling agents, distinct from traditional small-molecule drugs or larger protein hormones. Modulation implies subtle, targeted adjustment of function.
Mechanism
Peptides exert their effect by binding with high affinity to designated cell surface receptors, triggering defined intracellular cascades that can up-regulate growth hormone release or modify insulin sensitivity pathways. The short half-life often necessitates specific delivery methods to achieve sustained therapeutic modulation.
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