The targeted use of short chains of amino acids (peptides) as therapeutic agents to modulate specific physiological functions, often mimicking or enhancing natural signaling molecules. In hormonal wellness, this frequently involves optimizing growth hormone release or modulating appetite regulation pathways. These agents offer high specificity with potentially fewer systemic side effects than traditional hormones.
Origin
Derived from biochemistry and modern pharmacology, peptides represent a class of therapeutics bridging small molecules and large proteins. Their application in endocrinology leverages their ability to interact precisely with cell surface receptors.
Mechanism
Peptides operate by binding to specific membrane receptors, initiating intracellular signaling cascades that influence gene expression or cellular secretion patterns. For example, certain GHRH analogs stimulate the pituitary to increase endogenous growth hormone pulses. The mechanism relies on the peptide’s structural integrity and its specific affinity for the target receptor subtype.
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