Peptide Signaling Systems encompass the network of short-chain amino acid molecules, distinct from classical steroid hormones, that act as crucial intercellular messengers regulating processes like growth, satiety, and immune modulation. These peptides often exert rapid, localized effects by binding to specific surface receptors, initiating second messenger cascades. They represent a fine-tuning mechanism within the broader endocrine regulatory framework.
Origin
Derived from biochemistry, this term groups molecules based on their structure (peptides) and function (signaling). Its contemporary use in wellness science often refers to therapeutic applications of synthesized or naturally occurring regulatory peptides.
Mechanism
Peptides typically bind to membrane-bound receptors, activating G-proteins or tyrosine kinase pathways to rapidly alter cellular function without entering the nucleus. For example, growth hormone-releasing peptides (GHRPs) stimulate somatotrophs to release growth hormone, thereby influencing downstream anabolic signaling. The transient nature of peptide action allows for precise temporal control over physiological responses.
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