Peptide Sequence Communication is the precise method by which short chains of amino acids act as specific signaling molecules across endocrine and paracrine systems. These peptides transmit instructions between cells, often acting as hormones, neurotransmitters, or local growth factors that regulate complex physiological functions. This form of biological language is fundamental to hormonal regulation.
Origin
The origin lies in biochemistry and protein synthesis, focusing on the sequence-dependent function of short polypeptide chains. In the context of wellness science, it emphasizes the specificity derived from the amino acid arrangement, which dictates receptor binding affinity and subsequent biological effect. This contrasts with the broader class of steroid hormones.
Mechanism
Communication occurs when a specific peptide sequence binds to a cognate receptor, typically on the cell surface, initiating a rapid intracellular cascade, often involving second messengers like cAMP or calcium flux. For example, an insulin-like growth factor (IGF) peptide sequence binds its receptor to promote cellular uptake and anabolism. The exact sequence ensures that the message is delivered only to the intended cellular target, maintaining systemic order.
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