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Peptide Secretagogue Mechanism

Meaning

Peptide Secretagogue Mechanism describes the specific molecular pathway by which certain synthetic or naturally derived amino acid chains stimulate the release of an endogenous hormone from an endocrine gland. These peptides do not act as the replacement hormone itself; rather, they function as signaling molecules that bind to specific G-protein coupled receptors on the target cells, prompting the pulsatile secretion of the desired hormone. The most common application in hormonal health involves Growth Hormone-Releasing Peptides and their action on the pituitary somatotrophs to release growth hormone.