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Peptide Receptor Upregulation

Meaning

Peptide Receptor Upregulation is a physiological process where the density and sensitivity of specific cell surface receptors for peptide hormones and growth factors are deliberately increased. This clinical strategy is employed to enhance the cellular response to endogenous or administered peptides, effectively amplifying the biological signal without necessarily increasing the circulating hormone concentration. The upregulation leads to a more potent and efficient cellular communication system, improving overall tissue responsiveness.