What is the Origin of Peptide Pathway?

The term is rooted in biochemistry and endocrinology, defining a class of signaling molecules distinct from steroid or amine hormones. The "pathway" refers to the entire cascade, from the initial gene transcription and post-translational modification to the final signal transduction event at the target cell. Understanding these pathways is key to peptide therapeutics.

What is the Mechanism of Peptide Pathway?

Peptides are synthesized in ribosomes, processed in the endoplasmic reticulum and Golgi apparatus, and stored in secretory vesicles before being released via exocytosis. Upon release, they bind to high-affinity cell-surface receptors, initiating a second messenger cascade within the target cell. Examples include the hypothalamic-pituitary peptides like GnRH and TRH, as well as metabolic regulators like ghrelin and leptin.

Peptide Pathway ∞ Area

Peptide Pathway

Meaning

A specific, defined biological route involving the synthesis, secretion, transport, and receptor-mediated action of signaling peptides, which are short chains of amino acids that function as hormones or neurotransmitters. These pathways are integral to coordinating complex physiological processes, including metabolism, appetite regulation, and neuroendocrine communication. They represent a rapid and targeted form of intercellular communication.