Peptide Informational Transfer describes the specific mechanism by which a bioactive peptide, whether endogenous or exogenous, conveys a regulatory instruction to a distant target cell through molecular interaction. These peptides act as highly specific biological telecommunication signals within the body’s regulatory network. The transfer is characterized by high affinity binding to specific surface receptors. This precise interaction dictates the subsequent cellular response.
Origin
The term arises from peptide biology, where these short amino acid sequences are recognized as potent, localized, or systemic regulators of physiology. Its origin is in understanding the role of molecules like insulin or GLP-1 as messengers that bridge tissues.
Mechanism
The transfer process begins when the peptide ligand binds to its cognate transmembrane receptor, often leading to receptor dimerization and activation of associated intracellular signaling molecules. In some cases, the entire peptide-receptor complex is internalized, modulating downstream events directly within the cell nucleus or cytoplasm. This specific interaction triggers the desired biological cascade, such as gene expression or enzyme activation.
We use cookies to personalize content and marketing, and to analyze our traffic. This helps us maintain the quality of our free resources. manage your preferences below.
Detailed Cookie Preferences
This helps support our free resources through personalized marketing efforts and promotions.
Analytics cookies help us understand how visitors interact with our website, improving user experience and website performance.
Personalization cookies enable us to customize the content and features of our site based on your interactions, offering a more tailored experience.