This is a therapeutic modality that utilizes specific, short-chain amino acid sequences (peptides) to precisely signal and stimulate the body’s intrinsic repair and regenerative processes. These biologically active molecules act as targeted ligands, initiating cellular responses like tissue repair, anti-inflammation, or growth factor release. It represents a highly targeted approach to tissue and systemic renewal with reduced systemic burden.
Origin
The concept stems from the discovery of naturally occurring regulatory peptides and their subsequent development as pharmaceutical or clinical agents, merging the fields of endocrinology, biochemistry, and regenerative medicine. The term emphasizes the therapeutic use of these signaling molecules to restore youthful function.
Mechanism
Peptides function by binding to specific, high-affinity receptors on target cell membranes, which then activates downstream intracellular signaling cascades. For regeneration, this often involves stimulating the proliferation and differentiation of stem cells, promoting collagen synthesis, or inducing the release of endogenous growth hormone. The mechanism is characterized by a high degree of specificity and low systemic toxicity due to their natural signaling role.
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