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Peptide Degradation Pathways

Meaning

Peptide Degradation Pathways are the specific enzymatic processes within cells and the circulation responsible for the catabolism, or breakdown, of signaling peptides and proteins. These pathways are crucial for regulating the biological half-life and termination of the effects of peptide hormones, growth factors, and neuropeptides. Efficient and controlled degradation ensures that hormonal signals are precise and transient, preventing overstimulation or prolonged action. Clinical considerations often involve understanding these pathways to modulate the duration of action for therapeutic peptides.