This is a clinical modality involving the therapeutic use of short-chain amino acid compounds, known as peptides, which act as signaling molecules to selectively modulate or restore specific physiological functions at the cellular level. These bioregulators typically mimic or enhance the action of endogenous signaling peptides, targeting receptors to promote tissue repair, modulate immune function, or restore optimal endocrine communication. The therapy offers a highly targeted approach to complex systemic dysfunctions.
Origin
The therapy is rooted in the discovery of endogenous regulatory peptides and the understanding that many biological processes are controlled by these precise, informational molecules. Modern pharmacological advancements allow for the synthesis of bioidentical or modified peptides for clinical application. This approach represents a shift toward upstream regulation of cellular processes, focusing on communication rather than simply mass replacement.
Mechanism
The mechanism of action is receptor-mediated and highly specific. Administered peptides bind to cognate receptors on target cell membranes, initiating a cascade of intracellular signaling events that can modulate gene expression, enzyme activity, or cellular proliferation. For example, certain peptides can enhance growth hormone release, while others may improve mitochondrial efficiency or reduce chronic inflammation, thereby facilitating system redundancy restoration and promoting tissue homeostasis.
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