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Peptide Biocompatibility

Meaning

Peptide biocompatibility refers to the capacity of an administered therapeutic peptide to exist in contact with the body’s tissues and fluids without eliciting a significant, undesirable local or systemic adverse reaction. This concept is paramount in peptide therapy, encompassing factors such as immunogenicity, cytotoxicity, and the peptide’s susceptibility to enzymatic degradation. A high degree of biocompatibility ensures that the peptide can perform its intended regulatory or signaling function with minimal disruption to the host’s physiological environment.