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Pellet Hormone Delivery

Meaning

Pellet hormone delivery is a method of hormone replacement therapy where a small, compressed, bio-identical hormone implant is inserted subcutaneously, typically into the hip or buttocks area, to provide a sustained, continuous release of the hormone over several months. This delivery system bypasses the hepatic first-pass metabolism associated with oral administration, offering consistent, physiologic hormone levels in the circulation. It is a clinical option for patients seeking convenience and steady state hormone concentrations, although it requires a minor surgical procedure for insertion and removal. The slow-release profile aims to mimic the body’s natural endocrine secretion patterns.