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Peak Bone Mass Accrual

Meaning

Peak Bone Mass Accrual is the critical physiological process occurring primarily during childhood, adolescence, and early adulthood where the skeleton achieves its maximum density, strength, and structural integrity. This period, typically culminating around the third decade of life, is essential for determining an individual’s lifelong skeletal reserve and future susceptibility to fragility fractures and osteoporosis. Optimal accrual requires a complex, synergistic interplay of genetic predisposition, adequate nutrition, hormonal balance, and mechanical loading forces.