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Pdx-1 Transcription Factor

Meaning

Pdx-1, or Pancreatic and Duodenal Homeobox 1, is a crucial transcription factor protein that governs the development of the pancreas during embryogenesis and maintains the mature function of pancreatic beta cells. This nuclear protein is indispensable for regulating the expression of key genes, most notably insulin, which is vital for glucose homeostasis. Clinical research targets Pdx-1 expression as a potential mechanism to enhance beta cell mass and function in diabetes treatment strategies.