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PDC

Meaning

PDC, in the context of cellular metabolism and health, refers to the Pyruvate Dehydrogenase Complex, a massive, multi-enzyme assembly located within the mitochondrial matrix. This complex performs a critical, irreversible reaction that links the metabolic pathway of glycolysis to the citric acid cycle. Its proper function is indispensable for the efficient conversion of carbohydrates into acetyl-CoA, which then fuels the aerobic production of adenosine triphosphate (ATP), the cell’s primary energy currency.