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PCOS Phenotypes

Meaning

PCOS Phenotypes refer to the distinct clinical and biochemical presentations of Polycystic Ovary Syndrome (PCOS), which is a common, complex endocrine disorder affecting women of reproductive age. According to the Rotterdam criteria, PCOS is categorized into four major phenotypes based on the presence or absence of three key features: hyperandrogenism (HA), ovulatory dysfunction (OD), and polycystic ovarian morphology (PCOM). Recognizing these specific phenotypes is crucial for personalized clinical management, as the metabolic and reproductive risks vary significantly across the different presentations. This nuanced classification moves beyond a single diagnosis to tailor treatment for the individual patient.