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PCOS Pathophysiology

Meaning

PCOS pathophysiology is the study of the underlying disordered physiological processes that characterize Polycystic Ovary Syndrome (PCOS), a common and complex endocrine disorder in women. It is defined by a complex interplay of genetic predisposition, chronic hyperandrogenism, ovarian dysfunction, and frequently coexisting insulin resistance. This intricate web of systemic dysfunction results in the core clinical manifestations of anovulation, hirsutism, and the characteristic polycystic ovarian morphology observed on ultrasound. Understanding the precise pathophysiology is essential for developing targeted therapeutic interventions that address the multiple root causes of the syndrome effectively.