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Paternal Age

Meaning

Paternal Age refers to the age of the biological father at the time of conception, a factor now clinically recognized for its potential impact on reproductive outcomes and the genetic health of the offspring. While maternal age is traditionally the primary focus, advancing paternal age is associated with an increased risk of accumulating de novo genetic mutations in sperm. This clinical variable is considered a relevant, modifiable risk factor for certain neurodevelopmental, psychiatric, and genetic conditions in the child.