Question 1

What is the Meaning of PATAS Peptide?

Accepted Answer

PATAS Peptide, an acronym for Peptide derived of PKC Alpha Targeting AlmS, is a novel, first-in-class therapeutic peptide biologic currently under investigation for its potential to specifically target and reverse metabolic dysfunction within adipocytes. This compound is designed to restore the proper metabolic and endocrine physiology of fat cells, which is characteristically impaired in conditions of severe insulin resistance and Type 2 diabetes. It represents a promising, targeted approach to treat the underlying cellular pathology of metabolic disease.

Question 2

What is the Origin of PATAS Peptide?

Accepted Answer

The term is an acronym developed by the research group responsible for the peptide's discovery, explicitly detailing its molecular target and derivation. Its origin lies in advanced endocrinology and metabolic research, specifically following the elucidation of the molecular mechanisms of insulin resistance observed in rare genetic disorders like Alström syndrome. The compound's design involved a rational screening of alpha-helices to identify a sequence capable of disrupting a key inhibitory protein interaction in the adipocyte.

Question 3

What is the Mechanism of PATAS Peptide?

Accepted Answer

PATAS operates by specifically interfering with the inhibitory binding interaction between the ALMS1 protein and protein kinase C-α (PKCα) within the adipocyte cytoplasm. In dysfunctional fat cells, ALMS1 sequesters and inhibits PKCα, thereby blocking the necessary insulin signaling cascade required for glucose uptake. By disrupting the ALMS1-PKCα complex, the PATAS peptide restores PKCα activity, which in turn triggers insulin-independent glucose absorption and utilization in the fat cell, thereby improving systemic insulin sensitivity and ameliorating associated comorbidities.

PATAS Peptide

Meaning

Origin

Mechanism

Can Peptide Interventions Prevent the Progression of Insulin Resistance?

Provided by the clinical team
at 4Ever Young Miami Dadeland

-15% ∞ HRTIO15

Your protocol begins with a conversation.

Visit

Schedule Appointment

About

Med & Wellness

4Ever Young Miami Dadeland

Communication

+1 786-529-6686

Email Us

Opening Hours