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P3NP

Meaning

P3NP, or Procollagen Type III N-terminal Peptide, is a circulating biochemical fragment released during the synthesis and extracellular processing of Type III collagen, serving as a dynamic biomarker of tissue remodeling and fibrosis. In the domain of hormonal health, the measurement of P3NP is clinically valuable as an indirect indicator of the anabolic effects of Growth Hormone (GH) and Insulin-like Growth Factor-1 (IGF-1) on connective tissues, particularly bone and muscle. Elevated serum levels typically correlate with active collagen synthesis and a robust anabolic state.