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P-5-P

Meaning

Pyridoxal-5′-Phosphate, the biologically active coenzyme form of Vitamin B6, essential for numerous metabolic reactions, particularly those involving amino acid metabolism and neurotransmitter synthesis. This active form is crucial for clinical efficacy, as many individuals possess genetic polymorphisms that impair the conversion of pyridoxine to P-5-P. It directly supports the production of serotonin and GABA, key modulators of the stress response.