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Oxidative Stress Response

Meaning

Oxidative Stress Response is the collective, coordinated cellular and systemic reaction initiated in response to a critical imbalance between the rate of production of damaging reactive oxygen species (ROS) and the biological system’s inherent capacity to neutralize these reactive intermediates and repair the resulting molecular damage. This essential response involves the rapid activation of specific antioxidant defense enzymes and DNA repair mechanisms. Chronic, unmitigated oxidative stress is widely recognized as a primary molecular driver of cellular senescence, age-related pathology, and significant endocrine dysfunction.